Anti-TNFRSF17 MAb (Clone 19)-iFluor® 450 Succinimidyl Ester (WJY0-LS7094)

This product is comprised of an Chimeric Humanized Anti-TNFRSF17 IgG1-kappa/lambda (Clone 19) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

TARGET

Name
TNFRSF17

Alternative Names
BCM; BCMA; CD269; CD antigen CD269; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; TNFRSF13A

Overview
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

ANTIBODY

Overview
Chimeric Humanized Anti-TNFRSF17 IgG1-kappa/lambda (Clone 19)

Species Reactivity
Human

DYE

Name
iFluor® 450 Succinimidyl Ester

Color
Green

Excitation⁄Emission (nm)
451/502

Detection method
Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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