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- Blinatumomab-Coumarin
Blinatumomab-Coumarin (CAT#: ADC-FL-391)
This product is comprised of an anti-CD19 (scFv-kappa-heavy)-(scFv-heavy-kappa) antibody (Blinatumomab) labeled with Coumarin. Coumarin is a blue-fluorescent dye and it's excitation/emission is 387/470 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD19
- Alternative Names
- CD19; CD19 molecule; CD19 antigen; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4; B4; CVID3; MGC12802;
- Overview
- Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
- Overview
- Anti-CD19 (scFv-kappa-heavy)-(scFv-heavy-kappa) antibody, Blinatumomab
- Generic name
- Blinatumomab
- Species Reactivity
- Human
- Name
- Coumarin
- Color
- Blue
- Excitation⁄Emission (nm)
- 387/470
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-781 | Anti-CD19 (Blinatumomab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-777 | Anti-CD19 (Blinatumomab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-2517 | Anti-CD19 (Denintuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-776 | Anti-CD19 (Blinatumomab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-775 | Anti-CD19 (Taplitumomab paptox)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
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