This product is comprised of an anti-CD19 (scFv-kappa-heavy)-(scFv-heavy-kappa) antibody (Blinatumomab) labeled with Fluoresein. Fluoresein is a fluorescent dye and it's excitation/emission is 490/525 nm.
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.