ADC Toxins

Creative Biolabs offers highly potent toxins and toxin derivatives targeting a variety of cellular pathways, including microtubule assemble and dynamics (microtubule toxins), DNA biochemistry and structure (DNA toxins), and gene transcription (transcription toxins) … for antibody-drug conjugate (ADC) development.

ADC toxins target crucial intracellular pathways to induce cell death and they can be over 1000-fold more potent than chemo therapeutic agents. Creative Biolabs carriers a large selection of ADC toxins ranging from common auristatins, maytansinoids, calicheamicins to more innovative toxins such as amatoxins…. The toxins are of high purity (>95%) and defined structure as often characterized by LC-MS and ¹HNMR.