- Home
- Products
- Customized FluoroAb™
- APP
- Crenezumab-iFluor 546
Crenezumab-iFluor 546 (CAT#: ADC-FL-113)
This product is comprised of an anti-APP monoclonal antibody (Crenezumab) labeled with iFluor 546. iFluor 546 is a yellow-fluorescent dye and it's excitation/emission is 556/573 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1, Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG4-kappa antibody, Gantenerumab
- Generic name
- Crenezumab
- Species Reactivity
- Human
- Name
- iFluor 546
- Color
- Yellow
- Excitation⁄Emission (nm)
- 556/573
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-CTLA4 MAb (Clone 7)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10467)
- Anti-APP MAb (Clone 17)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS1083)
- Anti-MSLN MAb (Clone 2)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11215)
- Anti-MSLN MAb (Clone 6)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10231)
- Anti-CSF2 MAb (Clone 1)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS7885)
- Anti-FGFR2 MAb (Clone 7)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS15637)
- Anti-TNFRSF10B MAb (Clone 2)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8398)
- Anti-CD4 MAb (Clone 32)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10393)
- Anti-MSLN MAb (Clone 5)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3895)
- Anti-F3 MAb (Clone 12)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS862)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-113. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-702 | Anti-APP (Solanezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-707 | Anti-APP (Bapineuzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-706 | Anti-APP (Bapineuzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-711 | Anti-APP (Ponezumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-709 | Anti-APP (Bapineuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
