DM4 (CAT#: ADC-P-034)
ADCs Toxins, DM4 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
- Product Information
- CAS NO
- 799840-96-3
- Description
- ADCs Toxins, DM4 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
- Classification
- Microtubule Inhibitors
- Molecular Weight
- 780.37
- Purity
- 95%
Published Data
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