- Home
- Products
- Customized FluoroAb™
- C5
- Eculizumab-iFluor 488
Eculizumab-iFluor 488 (CAT#: ADC-FL-237)
This product is comprised of an anti-C5 monoclonal antibody (Eculizumab) labeled with iFluor 488. iFluor 488 is a green-fluorescent dye and it's excitation/emission is 490/525 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- C5
- Alternative Names
- C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
- Overview
- This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-C5 IgG2/G4-kappa antibody, Eculizumab
- Generic name
- Eculizumab
- Species Reactivity
- Human
- Name
- iFluor 488
- Color
- Green
- Excitation⁄Emission (nm)
- 490/525
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-CD19 MAb (Clone 10)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8246)
- Anti-IGF1R MAb (Clone 6)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12055)
- Anti-24P4C12 MAb (Clone 1)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS1931)
- Anti-TNF MAb (Clone 4)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5319)
- Anti-IL17A MAb (Clone 11)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15160)
- Anti-IL5RA MAb (Clone 2)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13650)
- Anti-CD33 MAb (Clone 12)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3944)
- Anti-CD72 MAb (Clone 1)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2093)
- Anti-ERBB2 MAb (Clone 28)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14404)
- Anti-TMEFF2 MAb (Clone 1)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS12752)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-237. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-739 | Anti-C5 (Pexelizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-728 | Anti-C5 (Eculizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-729 | Anti-C5 (Eculizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-735 | Anti-C5 (Pexelizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-731 | Anti-C5 (Eculizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
