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- MC-Val-Cit-PAB-carfilzomib
MC-Val-Cit-PAB-carfilzomib (CAT#: ADC-S-066)
Linker-Toxin SET, this set is made by carfilzomib conjugated to the lysosomally cleavable MC-vc-PAB linker. Carfilzomib is an irreversible proteasome inhibitor, which can irreversibly bind to and inhibit the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome and lead to cell cycle arrest, apoptosis, and inhibit tumor growth.
- Product Information
- CAS NO
- 2055896-83-6
- Description
- Linker-Toxin SET, this set is made by carfilzomib conjugated to the lysosomally cleavable MC-vc-PAB linker. Carfilzomib is an irreversible proteasome inhibitor, which can irreversibly bind to and inhibit the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome and lead to cell cycle arrest, apoptosis, and inhibit tumor growth.
- Molecular Weight
- 1275.56
- Purity
- 95%
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