MC-Val-Cit-PAB-carfilzomib (ADC-S-066)

Linker-Toxin SET, this set is made by carfilzomib conjugated to the lysosomally cleavable MC-vc-PAB linker. Carfilzomib is an irreversible proteasome inhibitor, which can irreversibly bind to and inhibit the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome and lead to cell cycle arrest, apoptosis, and inhibit tumor growth.

CAS NO
2055896-83-6

Description
Linker-Toxin SET, this set is made by carfilzomib conjugated to the lysosomally cleavable MC-vc-PAB linker. Carfilzomib is an irreversible proteasome inhibitor, which can irreversibly bind to and inhibit the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome and lead to cell cycle arrest, apoptosis, and inhibit tumor growth.

Molecular Weight
1275.56

Purity
95%

For Research Use Only. NOT FOR CLINICAL USE.

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