- Home
- Products
- DrugLnk™ Linker-Payloads
- Drug-linker Complexes
- Mc-vc-PAB-SN38
Mc-vc-PAB-SN38 (CAT#: ADC-S-023)
Linker-Toxin SET, this set is made by SN38 conjugated to the lysosomally cleavable dipeptide, valine-citrulline (vc) linker. SN-38 is the active metabolite of the topoisomerase-I (topo-I) inhibitor Irinotecan (CPT-11)and it stabilizes the complex between topo-I and DNA which collide with moving DNA replication forks, eventually leading to double stranded DNA damage.
- Product Information
- Description
- Linker-Toxin SET, this set is made by SN38 conjugated to the lysosomally cleavable dipeptide, valine-citrulline (vc) linker. SN-38 is the active metabolite of the topoisomerase-I (topo-I) inhibitor Irinotecan (CPT-11)and it stabilizes the complex between topo-I and DNA which collide with moving DNA replication forks, eventually leading to double stranded DNA damage.
- Molecular Weight
- 991.07
- Purity
- 95%
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-S-023. Click the button above to contact us or submit your feedback about this product.
Quick Links
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- GGVA-PAB-PNU (CAT#: WJY-0423-LS22)
- MC-Val-Cit-PAB-Auristatin E (CAT#: ADC-S-065)
- OSu-PEG4-vc-PAB- Duocarmycin SA (CAT#: ADC-S-011)
- SPP-DM1 (CAT#: ADC-S-050)
- DBCO-PEG4-AcBu-Calicheamicin (CAT#: WJY-0423-LS33)
- DBM-MMAF (CAT#: ADC-S-024)
- NHS-PEG2-NH-Xanomeline (CAT#: WJY-0423-LS46)
- AcLys-PABC-VC-Aur0101 (CAT#: ADC-S-057)
- mDPR-Val-Gln-PAB-MMAE (CAT#: WJY-0723-LS4)
- MC-PEG4-va-PAB-Exatecan (CAT#: WJY-0723-LS17)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
