- Home
- Products
- Customized FluoroAb™
- C5
- Pexelizumab-Fluoresein
Pexelizumab-Fluoresein (CAT#: ADC-FL-268)
This product is comprised of an anti-C5 scFv antibody (Pexelizumab) labeled with Fluoresein. Fluoresein is a fluorescent dye and it's excitation/emission is 490/525 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- C5
- Alternative Names
- C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
- Overview
- This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-C5 scFv antibody, Pexelizumab
- Generic name
- Pexelizumab
- Species Reactivity
- Human
- Name
- Fluoresein
- Excitation⁄Emission (nm)
- 490/525
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-268. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-733 | Anti-C5 (Eculizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-737 | Anti-C5 (Pexelizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-728 | Anti-C5 (Eculizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-732 | Anti-C5 (Eculizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-730 | Anti-C5 (Eculizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-IgG Fc MAb (Clone 6)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11336)
- Anti-IL6R MAb (Clone 6)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS9051)
- Anti-ERBB3 MAb (Clone 4)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6940)
- Anti-NCAM1 MAb (Clone 3)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3860)
- Anti-CFD MAb (Clone 5)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15069)
- Anti-CD5 MAb (Clone 8)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5811)
- Muromonab-iFluor 568 (CAT#: ADC-FL-601)
- Anti-IL6 MAb (Clone 8)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15190)
- Anti-CD38 MAb (Clone 4)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8812)
- Anti-CD19 MAb (Clone 21)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7079)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
