- Home
- Products
- Customized FluoroAb™
- C5
- Pexelizumab-Fluoresein
Pexelizumab-Fluoresein (CAT#: ADC-FL-268)
- TARGET
- ANTIBODY
- DYE
- Name
- C5
- Alternative Names
- C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
- Overview
- This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-C5 scFv antibody, Pexelizumab
- Generic name
- Pexelizumab
- Species Reactivity
- Human
- Name
- Fluoresein
- Excitation⁄Emission (nm)
- 490/525
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-268. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-734 | Anti-C5 (Pexelizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-737 | Anti-C5 (Pexelizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-736 | Anti-C5 (Pexelizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-728 | Anti-C5 (Eculizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-739 | Anti-C5 (Pexelizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-ERBB2 MAb (Clone 33)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11671)
- Anti-FLAG MAb (Clone 1)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS537)
- Anti-LTA MAb (Clone 5)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2923)
- Anti-LTA MAb (Clone 14)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4470)
- Anti-MYL MAb (Clone 16)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4693)
- Anti-RTN4 MAb (Clone 1)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5302)
- Anti-DLL3 MAb (Clone 9)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8603)
- Parsatuzumab-Bodipy FL (CAT#: ADC-FL-1128)
- Anti-PDCD1 MAb (Clone 4)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7603)
- Anti-ANGPTL3 MAb (Clone 1)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16161)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
