- Home
- Products
- Customized FluoroAb™
- C5
- Pexelizumab-iFluor 350
Pexelizumab-iFluor 350 (CAT#: ADC-FL-253)
This product is comprised of an anti-C5 scFv antibody (Pexelizumab) labeled with iFluor 350. iFluor 350 is a blue-fluorescent dye and it's excitation/emission is 346/442 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- C5
- Alternative Names
- C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
- Overview
- This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-C5 scFv antibody, Pexelizumab
- Generic name
- Pexelizumab
- Species Reactivity
- Human
- Name
- iFluor 350
- Color
- Blue
- Excitation⁄Emission (nm)
- 346/442
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-C5 MAb (Clone 24)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6285)
- Anti-HAVCR1 MAb (Clone 1)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5060)
- Anti-ITIH4 MAb (Clone 1)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS12650)
- Anti-SOST MAb (Clone 6)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12261)
- Anti-FAP MAb (Clone 2)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14386)
- Anti-EGFR MAb (Clone 25)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8541)
- Anti-PDCD1 MAb (Clone 22)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10696)
- Anti-PDCD1 MAb (Clone 9)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7608)
- Anti-CXCR4 MAb (Clone 2)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5120)
- Anti-MSTN MAb (Clone 11)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS9120)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-253. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-729 | Anti-C5 (Eculizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-731 | Anti-C5 (Eculizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-738 | Anti-C5 (Pexelizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-734 | Anti-C5 (Pexelizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-735 | Anti-C5 (Pexelizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
