- Home
- Products
- Customized FluoroAb™
- APP
- Ponezumab-Cy5
Ponezumab-Cy5 (CAT#: ADC-FL-195)
This product is comprised of an anti-APP monoclonal antibody (Ponezumab) labeled with Cy5. Cy5 is a far-red-fluorescent dye and it's excitation/emission is 649/666 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1, Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG2-kappa antibody, Ponezumab
- Generic name
- Ponezumab
- Species Reactivity
- Human
- Name
- Cy5
- Color
- Far-red
- Excitation⁄Emission (nm)
- 649/666
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-ITGB3 MAb (Clone 1)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14293)
- Anti-FOLR1 MAb (Clone 1)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS10989)
- Anti-PDCD1 MAb (Clone 24)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13774)
- Anti-CD33 MAb (Clone 16)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5639)
- Anti-TACSTD2 MAb (Clone 4)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14804)
- Anti-CCL11 MAb (Clone 3)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2633)
- Anti-CD79B MAb (Clone 13)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2391)
- Anti-CCL11 MAb (Clone 1)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS1696)
- Anti-MIF MAb (Clone 1)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9997)
- Anti-NGF MAb (Clone 1)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3751)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-195. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-714 | Anti-APP (Ponezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-708 | Anti-APP (Bapineuzumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-704 | Anti-APP (Bapineuzumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-706 | Anti-APP (Bapineuzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-705 | Anti-APP (Bapineuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
