- Home
- Products
- Customized FluoroAb™
- APP
- Ponezumab-Cy5
Ponezumab-Cy5 (CAT#: ADC-FL-195)
This product is comprised of an anti-APP monoclonal antibody (Ponezumab) labeled with Cy5. Cy5 is a far-red-fluorescent dye and it's excitation/emission is 649/666 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1, Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG2-kappa antibody, Ponezumab
- Generic name
- Ponezumab
- Species Reactivity
- Human
- Name
- Cy5
- Color
- Far-red
- Excitation⁄Emission (nm)
- 649/666
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-195. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-709 | Anti-APP (Bapineuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-703 | Anti-APP (Solanezumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-710 | Anti-APP (Ponezumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-713 | Anti-APP (Ponezumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-712 | Anti-APP (Ponezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-EDNRB MAb (Clone 2)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2068)
- Anti-S1P MAb (Clone 2)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13946)
- Anti-ERBB3 MAb (Clone 2)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3292)
- Anti-IL22 MAb (Clone 2)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4403)
- Anti-HGF MAb (Clone 6)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12034)
- Anti-CD19 MAb (Clone 19)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11691)
- Anti-CD3E MAb (Clone 10)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS1127)
- Anti-SOST MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6845)
- Anti-CA9 MAb (Clone 2)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS396)
- Anti-SOST MAb (Clone 5)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15336)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
