- Home
- Products
- Customized FluoroAb™
- APP
- Ponezumab-iFluor 532
Ponezumab-iFluor 532 (CAT#: ADC-FL-184)
This product is comprised of an anti-APP monoclonal antibody (Ponezumab) labeled with iFluor 532. iFluor 532 is a yellow-fluorescent dye and it's excitation/emission is 532/554 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1, Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG2-kappa antibody, Ponezumab
- Generic name
- Ponezumab
- Species Reactivity
- Human
- Name
- iFluor 532
- Color
- Yellow
- Excitation⁄Emission (nm)
- 532/554
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-CSF2 MAb (Clone 7)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7384)
- Anti-HBV MAb (Clone 3)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16965)
- Anti-CD6 MAb (Clone 1)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS10954)
- Anti-FOLH1 MAb (Clone 7)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9828)
- Anti-DLL4 MAb (Clone 1)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS12504)
- Anti-ITGAL MAb (Clone 1)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8338)
- Anti-B. anthracis PA MAb (Clone 1)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2272)
- Anti-Rabies Virus Glycoprotein MAb (Clone 5)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16937)
- Anti-EpCAM MAb (Clone 9)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2072)
- Anti-ITGB2 MAb (Clone 1)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS12955)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-184. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-704 | Anti-APP (Bapineuzumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-705 | Anti-APP (Bapineuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-710 | Anti-APP (Ponezumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-712 | Anti-APP (Ponezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-706 | Anti-APP (Bapineuzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
