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Rebeccamycin (CAT#: ADC-P-134)
ADCs Toxins, An antibiotic composed of a halogenated indolocarbazole chromophore linked via N-glycosidic bond to a glucose derivative. It intercalates into the DNA and is an inhibitor of topoisomerase I. L1210: IC50 = 100 nM (mouse); K562: IC50 = 200 nM (human); A549: IC50 = 300 nM (human); B16 melanoma cells: IC50 = 480 nM (mouse); P388 leukemia cells: IC50 = 500 nM
- Product Information
- CAS NO
- 93908-02-2
- Description
- ADCs Toxins, An antibiotic composed of a halogenated indolocarbazole chromophore linked via N-glycosidic bond to a glucose derivative. It intercalates into the DNA and is an inhibitor of topoisomerase I. L1210: IC50 = 100 nM (mouse); K562: IC50 = 200 nM (human); A549: IC50 = 300 nM (human); B16 melanoma cells: IC50 = 480 nM (mouse); P388 leukemia cells: IC50 = 500 nM
- Classification
- DNA Inhibitors
- Molecular Weight
- 570.38
- Purity
- 95%
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