SMCC-DM1 (CAT#: ADC-S-009)
Linker-Toxin SET, This set is made by DM1 conjugated to SMCC linker. DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
- Product Information
- CAS NO
- 1228105-51-8
- Description
- Linker-Toxin SET, This set is made by DM1 conjugated to SMCC linker. DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
- Molecular Weight
- 1072.6
- Purity
- 95%
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