CD40

CD40, also known as TNFRSF5, is a type I transmembrane protein. The molecular weight of CD40 is 48-kDa and it consists of a 193 amino acid (aa) extracellular domain, 21 aa leader sequence, 22 aa transmembrane domain, and a 62 aa intracellular domain in human (90 aa in mouse). There are 22 cysteine residues in the extracellular domain of CD40, and they are conserved between the members of the TNFR superfamily. Primitively, the expression of CD40 was found on B cells, and it is expressed by a variety of other cells, such as dendritic cells (DCs), platelets, monocytes, and macrophages, as well as by non-hematopoietic cells, including epithelial, myofibroblasts, fibroblasts, and endothelial cells.
CD40 serves as an important role in the pathogenesis of inflammation and autoimmunity. Besides, B cell CD40 directly activates cells, which enables to induce autoantibody production. CD154 is the ligand for CD40 and it is expressed on activated T cells and enables interactions with APC during the cognitive phase of the immune response, as well as directing effector T cell-dependent B cell activation. However, it has been reported that blocking CD40-CD154 interactions may either prevent or alleviate diseases, including insulin dependent diabetes mellitus, arthritis, and systemic lupus erythematosus.
Gene ID: 958
UniProt ID: P25942

Catalog Product name Similar to Antibody Linker Payload Data sheet Inquiry
ADC-W-902 Anti-CD40 (Teneliximab)-SMCC-DM1 ADC Chimeric Anti-CD40 IgG1 antibody, Teneliximab SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-903 Anti-CD40 (Teneliximab)-SPDB-DM4 ADC Chimeric Anti-CD40 IgG1 antibody, Teneliximab SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) Inquiry
ADC-W-904 Anti-CD40 (Teneliximab)-MC-MMAF ADC Chimeric Anti-CD40 IgG1 antibody, Teneliximab MC (maleimidocaproyl) MMAF Inquiry
ADC-W-905 Anti-CD40 (Teneliximab)-MC-Vc-PAB-MMAE ADC Chimeric Anti-CD40 IgG1 antibody, Teneliximab MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE Inquiry
ADC-W-906 Anti-CD40 (Teneliximab)-MC-Vc-PAB-SN38 ADC Chimeric Anti-CD40 IgG1 antibody, Teneliximab MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) SN-38 (7-ethyl-10-hydroxycamptothecin) Inquiry
ADC-W-907 Anti-CD40 (Teneliximab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC Chimeric Anti-CD40 IgG1 antibody, Teneliximab MC-Vc-PAB-DMEA-(PEG2) duocarmycin SA Inquiry
ADC-W-908 Anti-CD40 (Lucatumumab)-SMCC-DM1 ADC Human Anti-CD40 IgG1-kappa antibody, Lucatumumab SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-909 Anti-CD40 (Lucatumumab)-SPDB-DM4 ADC Human Anti-CD40 IgG1-kappa antibody, Lucatumumab SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) Inquiry
ADC-W-910 Anti-CD40 (Lucatumumab)-MC-MMAF ADC Human Anti-CD40 IgG1-kappa antibody, Lucatumumab MC (maleimidocaproyl) MMAF Inquiry
ADC-W-911 Anti-CD40 (Lucatumumab)-MC-Vc-PAB-MMAE ADC Human Anti-CD40 IgG1-kappa antibody, Lucatumumab MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE Inquiry
ADC-W-912 Anti-CD40 (Lucatumumab)-MC-Vc-PAB-SN38 ADC Human Anti-CD40 IgG1-kappa antibody, Lucatumumab MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) SN-38 (7-ethyl-10-hydroxycamptothecin) Inquiry
ADC-W-913 Anti-CD40 (Lucatumumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC Human Anti-CD40 IgG1-kappa antibody, Lucatumumab MC-Vc-PAB-DMEA-(PEG2) duocarmycin SA Inquiry
ADC-W-896 Anti-CD40 (Dacetuzumab)-SMCC-DM1 ADC Humanized Anti-CD40 IgG1 antibody, Dacetuzumab SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-897 Anti-CD40 (Dacetuzumab)-SPDB-DM4 ADC Humanized Anti-CD40 IgG1 antibody, Dacetuzumab SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) Inquiry
ADC-W-898 Anti-CD40 (Dacetuzumab)-MC-MMAF ADC Humanized Anti-CD40 IgG1 antibody, Dacetuzumab MC (maleimidocaproyl) MMAF Inquiry
ADC-W-899 Anti-CD40 (Dacetuzumab)-MC-Vc-PAB-MMAE ADC Humanized Anti-CD40 IgG1 antibody, Dacetuzumab MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE Inquiry
ADC-W-900 Anti-CD40 (Dacetuzumab)-MC-Vc-PAB-SN38 ADC Humanized Anti-CD40 IgG1 antibody, Dacetuzumab MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) SN-38 (7-ethyl-10-hydroxycamptothecin) Inquiry
ADC-W-901 Anti-CD40 (Dacetuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC Humanized Anti-CD40 IgG1 antibody, Dacetuzumab MC-Vc-PAB-DMEA-(PEG2) duocarmycin SA Inquiry
Catalog Product name Antibody Dye Detection Method Excitation/Emission (nm) Data sheet Inquiry
ADC-FL-739 Teneliximab-Alexa 350 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 350 Fluorescent 346/442 Inquiry
ADC-FL-740 Teneliximab-Alexa 405 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 405 Fluorescent 401/421 Inquiry
ADC-FL-741 Teneliximab-Alexa 488 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 488 Fluorescent 490/525 Inquiry
ADC-FL-742 Teneliximab-Alexa 532 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 532 Fluorescent 532/554 Inquiry
ADC-FL-743 Teneliximab-Alexa 546 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 546 Fluorescent 556/573 Inquiry
ADC-FL-744 Teneliximab-Alexa 555 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 555 Fluorescent 555/580 Inquiry
ADC-FL-745 Teneliximab-Alexa 568 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 568 Fluorescent 578/603 Inquiry
ADC-FL-746 Teneliximab-Alexa 594 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 594 Fluorescent 590/617 Inquiry
ADC-FL-747 Teneliximab-Alexa 647 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 647 Fluorescent 650/665 Inquiry
ADC-FL-748 Teneliximab-Alexa 680 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 680 Fluorescent 679/702 Inquiry
ADC-FL-749 Teneliximab-Alexa 750 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Alexa Fluor 750 Fluorescent 749/775 Inquiry
ADC-FL-750 Teneliximab-Bodipy FL Chimeric Anti-CD40 IgG1 antibody, Teneliximab Bodipy FL Fluorescent 503/512 Inquiry
ADC-FL-751 Teneliximab-Coumarin Chimeric Anti-CD40 IgG1 antibody, Teneliximab Coumarin Fluorescent 387/470 Inquiry
ADC-FL-752 Teneliximab-Cy3 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Cy3 Fluorescent 554/568 Inquiry
ADC-FL-753 Teneliximab-Cy5 Chimeric Anti-CD40 IgG1 antibody, Teneliximab Cy5 649/666 Inquiry
ADC-FL-754 Teneliximab-Fluoresein Chimeric Anti-CD40 IgG1 antibody, Teneliximab Fluoresein 490/525 Inquiry
ADC-FL-755 Teneliximab-OGreen Chimeric Anti-CD40 IgG1 antibody, Teneliximab Oregon green 501/526 Inquiry
ADC-FL-756 Teneliximab-PBlue Chimeric Anti-CD40 IgG1 antibody, Teneliximab Pafific blue 410/455 Inquiry
ADC-FL-757 Lucatumumab-Alexa 350 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 350 Fluorescent 346/442 Inquiry
ADC-FL-758 Lucatumumab-Alexa 405 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 405 Fluorescent 401/421 Inquiry
ADC-FL-759 Lucatumumab-Alexa 488 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 488 Fluorescent 490/525 Inquiry
ADC-FL-760 Lucatumumab-Alexa 532 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 532 Fluorescent 532/554 Inquiry
ADC-FL-761 Lucatumumab-Alexa 546 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 546 Fluorescent 556/573 Inquiry
ADC-FL-762 Lucatumumab-Alexa 555 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 555 Fluorescent 555/580 Inquiry
ADC-FL-763 Lucatumumab-Alexa 568 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 568 Fluorescent 578/603 Inquiry
ADC-FL-764 Lucatumumab-Alexa 594 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 594 Fluorescent 590/617 Inquiry
ADC-FL-765 Lucatumumab-Alexa 647 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 647 Fluorescent 650/665 Inquiry
ADC-FL-766 Lucatumumab-Alexa 680 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 680 Fluorescent 679/702 Inquiry
ADC-FL-767 Lucatumumab-Alexa 750 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Alexa Fluor 750 Fluorescent 749/775 Inquiry
ADC-FL-768 Lucatumumab-Bodipy FL Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Bodipy FL Fluorescent 503/512 Inquiry
ADC-FL-769 Lucatumumab-Coumarin Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Coumarin Fluorescent 387/470 Inquiry
ADC-FL-770 Lucatumumab-Cy3 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Cy3 Fluorescent 554/568 Inquiry
ADC-FL-771 Lucatumumab-Cy5 Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Cy5 649/666 Inquiry
ADC-FL-772 Lucatumumab-Fluoresein Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Fluoresein 490/525 Inquiry
ADC-FL-773 Lucatumumab-OGreen Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Oregon green 501/526 Inquiry
ADC-FL-774 Lucatumumab-PBlue Human Anti-CD40 IgG1-kappa antibody, Lucatumumab Pafific blue 410/455 Inquiry
ADC-FL-721 Dacetuzumab-Alexa 350 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 350 Fluorescent 346/442 Inquiry
ADC-FL-722 Dacetuzumab-Alexa 405 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 405 Fluorescent 401/421 Inquiry
ADC-FL-723 Dacetuzumab-Alexa 488 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 488 Fluorescent 490/525 Inquiry
ADC-FL-724 Dacetuzumab-Alexa 532 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 532 Fluorescent 532/554 Inquiry
ADC-FL-725 Dacetuzumab-Alexa 546 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 546 Fluorescent 556/573 Inquiry
ADC-FL-726 Dacetuzumab-Alexa 555 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 555 Fluorescent 555/580 Inquiry
ADC-FL-727 Dacetuzumab-Alexa 568 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 568 Fluorescent 578/603 Inquiry
ADC-FL-728 Dacetuzumab-Alexa 594 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 594 Fluorescent 590/617 Inquiry
ADC-FL-729 Dacetuzumab-Alexa 647 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 647 Fluorescent 650/665 Inquiry
ADC-FL-730 Dacetuzumab-Alexa 680 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 680 Fluorescent 679/702 Inquiry
ADC-FL-731 Dacetuzumab-Alexa 750 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Alexa Fluor 750 Fluorescent 749/775 Inquiry
ADC-FL-732 Dacetuzumab-Bodipy FL Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Bodipy FL Fluorescent 503/512 Inquiry
ADC-FL-733 Dacetuzumab-Coumarin Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Coumarin Fluorescent 387/470 Inquiry
ADC-FL-734 Dacetuzumab-Cy3 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Cy3 Fluorescent 554/568 Inquiry
ADC-FL-735 Dacetuzumab-Cy5 Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Cy5 649/666 Inquiry
ADC-FL-736 Dacetuzumab-Fluoresein Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Fluoresein 490/525 Inquiry
ADC-FL-737 Dacetuzumab-OGreen Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Oregon green 501/526 Inquiry
ADC-FL-738 Dacetuzumab-PBlue Humanized Anti-CD40 IgG1 antibody, Dacetuzumab Pafific blue 410/455 Inquiry
If you can’t find your product on this list? Please directly send email to

Online Inquiry
Name:
*Phone:
*E-mail Address:
*Products or Services Interested:
Company/Institution
Project Description:
*Verification Code:
Please input "biolabs"(case insensitive) as verification code.


Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.


Contact us
USA
 45-1 Ramsey Road, Shirley, NY 11967, USA
 Tel: 1-631-357-2254
 Fax: 1-631-207-8356
 Email:
Europe
Heidenkampsweg 58, 20097 Hamburg, Germany
 Tel: 44-207-097-1828
 Email:

Inquiry

Top