CD79b

CD79B (Cluster of Differentiation 79B, immunoglobulin-associated beta) is a B lymphocyte antigen receptor that is also known as B29, IGB, or AGM6. It is a cell surface localized B cell receptor (BCR) that contains one immunoglobulin-like V-type domain and one ITAM domain. In cooperation with CD79A, CD79B is involved in the initiation of downstream signal transduction cascade upon the activation by B-cell antigen receptor complex, during which it is phosphorylated. Subsequently, the activated B-cell antigen receptor complex is internalized and trafficked to late endosomes for antigen presentation.

Overexpression of CD79B is associated with lymphoma and its capacity for receptor mediated endocytosis renders CD79B an ideal target for the treatment of cancers such as leukemia by using ADC-based targeted immunotherapies.

Entrez Gene ID: 974
UniProt ID: P40259

Catalog Product name Similar to Antibody Linker Payload Data sheet Inquiry
ADC-W-030 Anti-CD79b (clone ch10D10)-Mc-MMAF ADC Anti-CD79b antibody, clone # ch10D10 Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-031 Anti-CD79b (clone ch10D10)-BMPEO-DM1 ADC Anti-CD79b antibody, clone # ch10D10 BMPEO (bis-maleimido-trioxyethylene glycol) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-032 Anti-CD79b (clone ch10D10)-Mc-VC-PABC-MMAE ADC Anti-CD79b antibody, clone # ch10D10 MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE (Monomethyl auristatin E) Inquiry
ADC-W-174 Anti-CD79b (clone ch2F2)-Mc-MMAF ADC Anti-CD79B antibody, clone # ch2F2 Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-168 Anti-CD79b (clone ch2F2)-SMCC-DM1 ADC Anti-CD79B antibody, clone # ch2F2 SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-173 Anti-CD79b (clone ch2F2)-Mc-MMAF ADC Anti-CD79B antibody, clone # ch2F7 Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-169 Anti-CD79b (clone hu2F2.D7)-SMCC-DM1 ADC Anti-CD79B antibody, clone # hu2F2.D7 SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-170 Anti-CD79b (clone hu2F2.D7)-BMPEO-DM1 ADC Anti-CD79B antibody, clone # hu2F2.D7 BMPEO (bis-maleimido-trioxyethylene glycol) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-171 Anti-CD79b (clone hu2F2.D7)-Mc-MMAF ADC Anti-CD79B antibody, clone # hu2F2.D7 Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-172 Anti-CD79b (clone hu2F2.D7)-Mc-vc-PABC-MMAE ADC Anti-CD79B antibody, clone # hu2F2.D7 MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE (Monomethyl auristatin E) Inquiry
ADC-W-033 Anti-CD79b (clone MA79b)-Mc-MMAF ADC Anti-CD79b antibody, clone # MA79b-HC(A118C) Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-034 Anti-CD79b (clone MA79b)-Mc-MMAF ADC Anti-CD79b antibody, clone # MA79b-LC(V205C) Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-222 Anti-CD79b (SN8)-SPP-DM1 ADC Anti-CD79B IgG1 Antibody, SN8 SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-223 Anti-CD79b (SN8)-MCC-DM1 ADC Anti-CD79B IgG1 Antibody, SN8 MCC (Maleimidomethyl cyclohexane-1-carboxylate) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-224 Anti-CD79b (SN8)-Mc-VC-PABC-MMAE ADC Anti-CD79B IgG1 Antibody, SN8 MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE (Monomethyl auristatin E) Inquiry
ADC-W-225 Anti-CD79b (SN8)-Mc-MMAF ADC Anti-CD79B IgG1 Antibody, SN8 Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-237 Anti-CD79b (clone 10D10)-MCC-DM1 ADC Chimeric Anti-CD79B Antibody, clone # 10D10 MCC (Maleimidomethyl cyclohexane-1-carboxylate) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-024 Anti-CD79b (clone huMA79b.v18)-Mc-MMAF ADC Humanized Anti-CD79b antibody, clone # huMA79b.v18 Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-025 Anti-CD79b (clone huMA79b.v18)-BMPEO-DM1 ADC Humanized Anti-CD79b antibody, clone # huMA79b.v18 BMPEO (bis-maleimido-trioxyethylene glycol) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-026 Anti-CD79b (clone huMA79b.v18)-Mc-vc-PABC-MMAE ADC Humanized Anti-CD79b antibody, clone # huMA79b.v18 MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE (Monomethyl auristatin E) Inquiry
ADC-W-027 Anti-CD79b (clone huMA79b.v28)-Mc-MMAF ADC Humanized Anti-CD79b antibody, clone # huMA79b.v18 Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-028 Anti-CD79b (clone huMA79b.v28)-BMPEO-DM1 ADC Humanized Anti-CD79b antibody, clone # huMA79b.v18 BMPEO (bis-maleimido-trioxyethylene glycol) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-029 Anti-CD79b (clone huMA79b.v28)-Mc-VC-PABC-MMAE ADC Humanized Anti-CD79b antibody, clone # huMA79b.v18 MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE (Monomethyl auristatin E) Inquiry
ADC-W-2554 Anti-CD79B (Polatuzumab )-SMCC-DM1 ADC Humanized Anti-CD79B IgG1-kappa antibody, Polatuzumab SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-2555 Anti-CD79B (Polatuzumab )-SPDB-DM4 ADC Humanized Anti-CD79B IgG1-kappa antibody, Polatuzumab SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) Inquiry
ADC-W-2556 Anti-CD79B (Polatuzumab )-MC-MMAF ADC Humanized Anti-CD79B IgG1-kappa antibody, Polatuzumab MC (maleimidocaproyl) MMAF Inquiry
ADC-W-2557 Anti-CD79B (Polatuzumab )-MC-Vc-PAB-MMAE ADC Humanized Anti-CD79B IgG1-kappa antibody, Polatuzumab MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE Inquiry
ADC-W-2558 Anti-CD79B (Polatuzumab )-MC-Vc-PAB-SN38 ADC Humanized Anti-CD79B IgG1-kappa antibody, Polatuzumab MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) SN-38 (7-ethyl-10-hydroxycamptothecin) Inquiry
ADC-W-2559 Anti-CD79B (Polatuzumab )-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC Humanized Anti-CD79B IgG1-kappa antibody, Polatuzumab MC-Vc-PAB-DMEA-(PEG2) duocarmycin SA Inquiry
ADC-W-527 Anti-CD79B-MCC-DM1 ADC Humanized Anti-CD79B lgG1 Antibody Mcc (Maleimidomethyl cyclohexane-1-carboxylate) DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
ADC-W-528 Anti-CD79B-Mc-MMAF ADC Humanized Anti-CD79B lgG1 Antibody Mc (maleimidocaproyl) MMAF (Monomethyl auristatin F) Inquiry
ADC-W-379  Anti-CD79B (Polatuzumab)-VC-MMAE ADC Humanized Anti-CD79B lgG1 Antibody, Polatuzumab VC (valine-citrulline) MMAE (Monomethyl auristatin E) Inquiry
ADC-W-380 Anti-CD79B (Polatuzumab)-Mc-VC-PABC-MMAE ADC Humanized Anti-CD79B lgG1 Antibody, Polatuzumab MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE (Monomethyl auristatin E) Inquiry
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