SLIT and NTRK like family member 6 (SLITRK6), also known as DFNMYP, is an integral membrane protein. Mature human SLITRK6 is a type I transmembrane protein that contains an extracellular domain (ECD) with a cytoplasmic region. The SLITRK6 protein is featured by two N-terminal leucine-rich repeat domains and a C-terminal region.

Previous studies have shown that SLITRK6 is widely expressed in the embryo. It plays essential roles in the induction of neurotrophin expression from cells, which is a process that is required for normal hearing and vision. The mutation or abnormality of the SLITRK6 gene is the cause of myopia and deafness and it is also associated with various type of cancers, considering its high expression level in multiple epithelial tumors, including bladder, breast, lung cancers as well as in glioblastoma

Entrez Gene ID: 84189
UniProt ID: Q9H5Y7

Catalog Product name Similar to Antibody Linker Payload Data sheet Inquiry
ADC-W-489  Anti-SLITRK6-MMAE ADC AGS15E Human Anti-SLITRK6 lgG2 Antibody protease-cleavable linker MMAE (Monomethyl auristatin E) Inquiry
ADC-W-435 Anti-SLITRK6 (clone AGS15)-Mc-VC-MMAE ADC Human Anti-SLITRK6 lgG2 Antibody, clone # AGS15 mc-VC (maleimidocaproyl-valine-citrulline) MMAE (Monomethyl auristatin E) Inquiry
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