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- Teplizumab-iFluor 405
Teplizumab-iFluor 405 (CAT#: ADC-FL-542)
- TARGET
- ANTIBODY
- DYE
- Name
- CD3D
- Alternative Names
- CD3D; CD3d molecule, delta (CD3-TCR complex); CD3d antigen, delta polypeptide (TiT3 complex) , T3D; T-cell surface glycoprotein CD3 delta chain; CD3 delta; OKT3, delta chain; CD3 antigen, delta subunit; T-cell receptor T3 delta chain; CD3d antigen, delta polypeptide (TiT3 complex); T3D; CD3-DELTA
- Overview
- The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
- Overview
- Humanized Anti-CD3D IgG1-kappa antibody, Teplizumab
- Generic name
- Teplizumab
- Species Reactivity
- Human
- Name
- iFluor 405
- Color
- Blue
- Excitation⁄Emission (nm)
- 401/421
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-832 | Anti-CD3D (Teplizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-834 | Anti-CD3D (Teplizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-830 | Anti-CD3D (Teplizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-835 | Anti-CD3D (Teplizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-831 | Anti-CD3D (Teplizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
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