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- Toralizumab-Cy5
Toralizumab-Cy5 (CAT#: ADC-FL-807)
This product is comprised of an anti-CD40LG monoclonal antibody (Toralizumab) labeled with cy5. cy5 is a far-red-fluorescent dye and it's excitation/emission is 649/666 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD40LG
- Alternative Names
- CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; internalized inside cells, the cytosol provides reducing environment including intracellular enzyme protein disulfide isomerase, or similar enzymes, drugs can be released.
- Overview
- The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
- Overview
- Humanized Anti-CD40L IgG1-kappa antibody, Toralizumab
- Generic name
- Toralizumab
- Species Reactivity
- Human
- Name
- Cy5
- Color
- Far-red
- Excitation⁄Emission (nm)
- 649/666
For Research Use Only. NOT FOR CLINICAL USE.
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2446 | Anti-CD40LG (Dapirolizumab pegol)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-919 | Anti-CD40LG (Ruplizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-920 | Anti-CD40LG (Toralizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-2447 | Anti-CD40LG (Dapirolizumab pegol)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-924 | Anti-CD40LG (Toralizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
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