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- Toralizumab-Fluoresein
Toralizumab-Fluoresein (CAT#: ADC-FL-808)
This product is comprised of an anti-CD40LG monoclonal antibody (Toralizumab) labeled with Fluoresein. Fluoresein is a fluorescent dye and it's excitation/emission is 490/525 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD40LG
- Alternative Names
- CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; internalized inside cells, the cytosol provides reducing environment including intracellular enzyme protein disulfide isomerase, or similar enzymes, drugs can be released.
- Overview
- The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
- Overview
- Humanized Anti-CD40L IgG1-kappa antibody, Toralizumab
- Generic name
- Toralizumab
- Species Reactivity
- Human
- Name
- Fluoresein
- Excitation⁄Emission (nm)
- 490/525
For Research Use Only. NOT FOR CLINICAL USE.
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-924 | Anti-CD40LG (Toralizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-2446 | Anti-CD40LG (Dapirolizumab pegol)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-921 | Anti-CD40LG (Toralizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-922 | Anti-CD40LG (Toralizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-917 | Anti-CD40LG (Ruplizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
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