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- Altumomab-iFluor 350
Altumomab-iFluor 350 (CAT#: ADC-FL-937)
This product is comprised of an anti-CEACAM5 monoclonal antibody (Altumomab) labeled with iFluor 350. iFluor 350 is a blue-fluorescent dye and it's excitation/emission is 346/442 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CEACAM5
- Alternative Names
- CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100; DKFZp781M2392;
- Overview
- This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-CEACAM5 IgG1 antibody, altumomab
- Generic name
- Altumomab
- Species Reactivity
- Human
- Name
- iFluor 350
- Color
- Blue
- Excitation⁄Emission (nm)
- 346/442
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-971 | Anti-CEACAM5 (Altumomab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-2582 | Anti-CEACAM5-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-472 | Anti-CEACAM5-Phy-lys-SN-38 ADC | Phy-lys (Phenylalanine-lysine) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-969 | Anti-CEACAM5 (Altumomab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-970 | Anti-CEACAM5 (Altumomab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
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