- Home
- Products
- Customized FluoroAb™
- APP
- Anti-APP MAb (Clone 12)-iFluor® 460 Succinimidyl Ester
Anti-APP MAb (Clone 12)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS7813)
This product is comprised of an Humanized Anti-APP IgG2-kappa (Clone 12) labeled with iFluor® 460 Succinimidyl Ester. iFluor® 460 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1; Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG2-kappa (Clone 12)
- Species Reactivity
- Human
- Name
- iFluor® 460 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 468/493
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-HGF MAb (Clone 6)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16648)
- Anti-SOST MAb (Clone 2)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8384)
- Anti-MYL MAb (Clone 15)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16996)
- Anti-TNFRSF8 MAb (Clone 2)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS359)
- Anti-VTCN1 MAb (Clone 2)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5663)
- Anti-IL5 MAb (Clone 3)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4419)
- Anti-F3 MAb (Clone 6)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS509)
- Anti-VEGFA MAb (Clone 15)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS3092)
- Anti-CTAA16.88 MAb (Clone 2)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12346)
- Anti-IGF1 MAb (Clone 4)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15125)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS7813. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-707 | Anti-APP (Bapineuzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-705 | Anti-APP (Bapineuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-703 | Anti-APP (Solanezumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-713 | Anti-APP (Ponezumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-712 | Anti-APP (Ponezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
