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Anti-CCL2 MAb (Clone 3)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7248)

This product is comprised of an Human Anti-CCL2 IgG1-kappa (Clone 3) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

  • TARGET
  • ANTIBODY
  • DYE
  • Name
  • CCL2
  • Alternative Names
  • CCL2; chemokine (C-C motif) ligand 2; SCYA2; small inducible cytokine A2 (monocyte chemotactic protein 1; homologous to mouse Sig je); C-C motif chemokine 2; GDCF 2; HC11; MCAF; MCP 1; MCP1; MGC9434; monocyte chemoattractant protein 1; monocyte chemotactic and activating factor; monocyte chemotactic protein 1; homologous to mouse Sig je; monocyte secretory protein JE; small inducible cytokine subfamily A (Cys Cys); member 2; SMC CF; small-inducible cytokine A2; monocyte chemoattractant protein-1; small inducible cytokine subfamily A (Cys-Cys); member 2; small inducible cytokine A2 (monocyte chemotactic protein 1; homologous to mouse Sig-je); MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30;
  • Overview
  • This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
  • Overview
  • Human Anti-CCL2 IgG1-kappa (Clone 3)
  • Species Reactivity
  • Human
  • Name
  • iFluor® 450 Succinimidyl Ester
  • Color
  • Green
  • Excitation⁄Emission (nm)
  • 451/502
  • Detection method
  • Fluorescent

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ADC-W-752 Anti-CCL2 (Carlumab)-SMCC-DM1 ADC SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)

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