Anti-IL17A MAb (Clone 3)-iFluor® 450 Succinimidyl Ester (WJY0-LS6944)

This product is comprised of an Humanized Anti-IL17A IgG1-kappa antibody (Clone 3) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

TARGET

Name
IL17A

Alternative Names
IL17a

Overview
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

ANTIBODY

Overview
Humanized Anti-IL17A IgG1-kappa antibody (Clone 3)

Species Reactivity
Human

DYE

Name
iFluor® 450 Succinimidyl Ester

Color
Green

Excitation⁄Emission (nm)
451/502

Detection method
Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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