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- Anti-IL17A MAb (Clone 5)-iFluor® 514 Succinimidyl Ester
Anti-IL17A MAb (Clone 5)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12078)
- TARGET
- ANTIBODY
- DYE
- Name
- IL17A
- Alternative Names
- IL17a
- Overview
- The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
- Overview
- Humanized Anti-IL17A IgG4-kappa (Clone 5)
- Species Reactivity
- Human
- Name
- iFluor® 514 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 511/527
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2392 | Anti-IL17A (Bimekizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-2286 | Anti-IL17A (Perakizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-2284 | Anti-IL17A (Perakizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1314 | Anti-IL17A (Secukinumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-2391 | Anti-IL17A (Bimekizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
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