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- Anti-ITGA2 MAb (Clone 2)-iFluor® 440 Succinimidyl Ester
Anti-ITGA2 MAb (Clone 2)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5979)
This product is comprised of an Chimeric Anti-ITGA2 Fab-G1-kappa (Clone 2) labeled with iFluor® 440 Succinimidyl Ester. iFluor® 440 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- ITGA2
- Alternative Names
- ITGA2; BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2; integrin subunit alpha 2
- Overview
- Integrin alpha-2, or CD49b (cluster of differentiation 49b), is a protein which in humans is encoded by the CD49b gene. The CD49b protein is an integrin alpha subunit. It makes up half of the α2β1 integrin duplex. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface-mediated signalling
- Overview
- Chimeric Anti-ITGA2 Fab-G1-kappa (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 440 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 434/480
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-1456 | Anti-ITGA2 (Vatelizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1454 | Anti-ITGA2 (Vatelizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1457 | Anti-ITGA2 (Vatelizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1458 | Anti-ITGA2 (Vatelizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1455 | Anti-ITGA2 (Vatelizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
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