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- Anti-ITGA5 MAb (Clone 2)-iFluor® 450 Succinimidyl Ester
Anti-ITGA5 MAb (Clone 2)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7522)
- TARGET
- ANTIBODY
- DYE
- Name
- ITGA5
- Alternative Names
- ITGA5; CD49e; FNRA; VLA5A; VLA-5; integrin subunit alpha 5
- Overview
- Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
- Overview
- Chimeric Anti-ITGA5 IgG4 (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 450 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 451/502
- Detection method
- Fluorescent
Published Data
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Scientific Resources
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1478 | Anti-ITGA5 (Volociximab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1483 | Anti-ITGA5 (Volociximab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1482 | Anti-ITGA5 (Volociximab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1480 | Anti-ITGA5 (Volociximab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1481 | Anti-ITGA5 (Volociximab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
For Research Use Only. NOT FOR CLINICAL USE.
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