Anti-LAMP1 MAb (Clone 2)-iFluor® 460 Succinimidyl Ester (WJY0-LS7972)

This product is comprised of an Humanized Anti-LAMP1-antibody (Clone 2) labeled with iFluor® 460 Succinimidyl Ester. iFluor® 460 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

TARGET

Name
LAMP1

Alternative Names
LAMP1; CD107a; LAMPA; LGP120; lysosomal associated membrane protein 1

Overview
Lysosomal associated membrane protein 1 (LAMP-1), also known as lysosomal associated membrane glycoprotein 1 and CD107a (differentiation cluster 107a), is a protein encoded by the LAMP1 gene in the human body. The human LAMP1 gene is located on the long arm (q) of chromosome 13 and is located in region 3, band 4 (13q34).Lysosomal-associated membrane protein 1 is a glycoprotein from the lysosomal-associated membrane glycoprotein family. LAMP-1 glycoprotein is a type I transmembrane protein, expressed at high or moderate levels in at least 76 different normal tissue cell types. It is mainly located on the lysosomal membrane, and plays a role in providing carbohydrate ligand to selectin. CD107a has also been shown to be a degranulation marker for lymphocytes (eg CD8 + and NK cells). and may play a role in the differentiation and metastasis of tumor cells.

ANTIBODY

Overview
Humanized Anti-LAMP1-antibody (Clone 2)

Species Reactivity
Human

DYE

Name
iFluor® 460 Succinimidyl Ester

Color
Green

Excitation⁄Emission (nm)
468/493

Detection method
Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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