- Home
- Products
- Customized FluoroAb™
- NOTCH1
- Anti-NOTCH1 MAb (Clone 2)-iFluor® 350 Succinimidyl Ester
Anti-NOTCH1 MAb (Clone 2)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS1637)
- TARGET
- ANTIBODY
- DYE
- Name
- NOTCH1
- Alternative Names
- Notch 1; Translocation-Associated Notch Protein TAN-1; TAN1; HN1; Notch (Drosophila) Homolog 1 (Translocation-Associated); Notch Homolog 1; Translocation-Associated (Drosophila); Notch Homolog 1; Translocation-Associated;
- Overview
- This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]
- Overview
- Humanized Anti-NOTCH1 IgG2-lambda (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 350 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 345/450
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS1637. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2365 | Anti-NOTCH1 (Brontictuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-2361 | Anti-NOTCH1 (Brontictuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-2360 | Anti-NOTCH1 (Brontictuzumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-2362 | Anti-NOTCH1 (Brontictuzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-2364 | Anti-NOTCH1 (Brontictuzumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-IL2RA MAb (Clone 9)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8751)
- Anti-NGF MAb (Clone 4)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12199)
- Gavilimomab-iFluor 750 (CAT#: ADC-FL-209)
- Anti-CD3E MAb (Clone 1)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9400)
- Anti-CD28 MAb (Clone 2)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16162)
- Anti-SLAMF6 MAb (Clone 2)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6544)
- Anti-MST1R MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6611)
- Parsatuzumab-iFluor 532 (CAT#: ADC-FL-1120)
- Anti-MUC16 MAb (Clone 7)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9697)
- Anti-IL22 MAb (Clone 3)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS9018)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
