This product is comprised of an Chimeric Anti-SDC1 IgG4 antibody (Clone 1) labeled with iFluor® 405 Succinimidyl Ester. iFluor® 405 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 403/427 nm.
TARGET
- Alternative Names
- SDC1; CD138; SDC; SYND1; syndecan; syndecan 1
- Overview
- Syndecan 1 is a protein encoded by the SDC1 gene in humans. This protein is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the Syndecan proteoglycan family. Syndecan-1 protein plays the role of integral membrane protein, and participates in cell proliferation, cell migration and cell-matrix interaction through its extracellular matrix protein receptors. Syndecan-1 is a sponge of growth factors and chemokines, is mainly bound by heparan sulfate chains. Syndecans-mediated internalization of HIV-1 tat protein requires cell binding, cell signaling, cytoskeletal organization and Syndecan receptors.Altered syndecan-1 expression has been detected in several different tumor types. Syndecan 1 may be a marker of plasma cells.
ANTIBODY
- Overview
- Chimeric Anti-SDC1 IgG4 antibody (Clone 1)
DYE
- Name
- iFluor® 405 Succinimidyl Ester
- Excitation⁄Emission (nm)
- 403/427
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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