This product is comprised of an Humanized Anti-TNFRSF10B IgG1-kappa (Clone 12) labeled with iFluor® 405 Succinimidyl Ester. iFluor® 405 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 403/427 nm.
TARGET
- Alternative Names
- TRICK2A; TRICK2B; KILLER; TRAILR2; TNF-related apoptosis-inducing ligand receptor 2; DR5; CD antigen CD262; TRICK2; CD262; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TRAIL-R2; TRAIL receptor 2; TRICKB; ZTNFR9
- Overview
- The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
ANTIBODY
- Overview
- Humanized Anti-TNFRSF10B IgG1-kappa (Clone 12)
DYE
- Name
- iFluor® 405 Succinimidyl Ester
- Excitation⁄Emission (nm)
- 403/427
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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