Bertilimumab-PBlue (ADC-FL-306)

This product is comprised of an anti-CCL11 monoclonal antibody (Bertilimumab) labeled with Pacific blue. Pacific blue is a blue-fluorescent dye and it's excitation/emission is 410/455 nm.

 TARGET

  • Name
  • CCL11
  • Alternative Names
  • CCL11; chemokine (C-C motif) ligand 11; SCYA11, small inducible cytokine subfamily A (Cys Cys), member 11 (eotaxin); eotaxin; eotaxin 1; MGC22554; eotaxin-1; C-C motif chemokine 11; small-inducible cytokine A11; eosinophil chemotactic protein;
  • Overview
  • This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamiliesd the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal.

 ANTIBODY

  • Overview
  • Human Anti-CCL11 IgG4-kappa antibody, Bertilimumab
  • Generic name
  • Bertilimumab
  • Species Reactivity
  • Human

 DYE

  • Name
  • Pafific blue
  • Color
  • Blue
  • Excitation⁄Emission (nm)
  • 410/455

For Research Use Only. NOT FOR CLINICAL USE.


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