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- DBCO-PEG4-Ahx-DM1
DBCO-PEG4-Ahx-DM1 (CAT#: ADC-S-003)
Linker-Toxin SET, This set is made by DM1 conjugated to DBCO-PEG4-Ahx linker. DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
- Product Information
- Description
- Linker-Toxin SET, This set is made by DM1 conjugated to DBCO-PEG4-Ahx linker. DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
- Molecular Weight
- 1297.9
- Purity
- 95%
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