lampalizumab-Fluoresein (ADC-FL-988)

This product is comprised of an anti-CFD Fab' fragment (lampalizumab) labeled with Fluoresein. Fluoresein is a fluorescent dye and it's excitation/emission is 490/525 nm.

 TARGET

  • Name
  • CFD
  • Alternative Names
  • CFD; complement factor D (adipsin); D component of complement (adipsin) , DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD; ADIPSIN;
  • Overview
  • This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.

 ANTIBODY

  • Overview
  • Chimeric Anti-CFD IgG1-Fab’ fragment, lampalizumab
  • Generic name
  • lampalizumab
  • Species Reactivity
  • Human

 DYE

  • Name
  • Fluoresein
  • Excitation⁄Emission (nm)
  • 490/525

For Research Use Only. NOT FOR CLINICAL USE.


Related Products


Online Inquiry
Name:
*Phone:
*E-mail Address:
*Products or Services Interested:
Company/Institution
Project Description:









Customized FluoroAb™

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.

Contact us
USA
 
 Tel:
 Fax:
 Email:
Europe
 
 Tel:
 Email:
Germany
 
 Tel:
 Email:


Inquiry

Top