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MMAF (CAT#: ADC-P-020)

ADCs cytotoxin, Monomethylauristatin F(MMAF) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than MMAE; antibody drug cytotoxin.

  • Product Information
  • CAS NO
  • 745017-94-1
  • Description
  • ADCs cytotoxin, Monomethylauristatin F(MMAF) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than MMAE; antibody drug cytotoxin.
  • Classification
  • Microtubule Inhibitors
  • Molecular Weight
  • 731.96
  • Purity
  • 95%

For Research Use Only. NOT FOR CLINICAL USE.

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Customer Reviews FAQ
def-person
Excellent
We utilized MMAF in our ADC development, and its antitubulin properties greatly enhanced the cytotoxicity of our conjugates. It's an essential component for improving targeted therapies.
def-person
Excellent
In our ADC research, MMAF provided targeted cytotoxicity with manageable potency, ensuring efficient drug delivery while minimizing off-target effects. It contributed to more precise cancer treatment models.
def-person
Excellent
MMAF was crucial in our cytotoxicity assays, helping to block cell division at the tubulin polymerization stage. Its role in cell cycle inhibition was evident across different cancer cell lines.
def-person
Excellent
Our lab incorporated MMAF into antibody-drug conjugates, and its ability to block tubulin polymerization translated into enhanced cytotoxicity in target cells. This made it an excellent choice for ADC development.
def-person
Excellent
We tested MMAF in various cell lines, and its ability to inhibit cell division was consistent. Its lower cytotoxicity compared to MMAE allowed for more controlled experiments without compromising efficacy.

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