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- Mogamulizumab-iFluor 750
Mogamulizumab-iFluor 750 (CAT#: ADC-FL-335)
This product is comprised of an anti-CCR4 monoclonal antibody (Mogamulizumab) labeled with iFluor 750. iFluor 750 is a near-IR-fluorescent dye and it's excitation/emission is 749/775 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CCR4
- Alternative Names
- CCR4; chemokine (C-C motif) receptor 4; C-C chemokine receptor type 4; CC CKR 4; CD194; ChemR13; CKR4; CMKBR4; k5 5; CCR-4; C-C CKR-4; chemokine (C-C) receptor 4; K5-5; CC-CKR-4; HGCN:14099; MGC88293;
- Overview
- The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
- Overview
- Humanized Anti-CCR4 IgG1-kappa antibody, Mogamulizumab
- Generic name
- Mogamulizumab
- Species Reactivity
- Human
- Name
- iFluor 750
- Color
- Near-IR
- Excitation⁄Emission (nm)
- 749/775
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-758 | Anti-CCR4 (Mogamulizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-763 | Anti-CCR4 (Mogamulizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-759 | Anti-CCR4 (Mogamulizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-761 | Anti-CCR4 (Mogamulizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-762 | Anti-CCR4 (Mogamulizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
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