Linker-Toxin SET, this set is made by DM4 conjugated to non-cleavable SMCC linker. DM4 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubule.
- Description
- Linker-Toxin SET, this set is made by DM4 conjugated to non-cleavable SMCC linker. DM4 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubule.
For Research Use Only. NOT FOR CLINICAL USE.
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