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- Sulesomab-iFluor 647
Sulesomab-iFluor 647 (CAT#: ADC-FL-963)
This product is comprised of an anti-CEACAM6 Fab' fragment (Sulesomab) labeled with iFluor 647. iFluor 647 is a far-red-fluorescent dye and it's excitation/emission is 650/665 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CEACAM6
- Alternative Names
- CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); NCA; carcinoembryonic antigen-related cell adhesion molecule 6; CD66c; normal cross-reacting antigen; non-specific crossreacting antigen; CEAL;
- Overview
- This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
- Overview
- Humanized Anti-CEACAM6 IgG1-Fab’ fragment, Sulesomab
- Generic name
- Sulesomab
- Species Reactivity
- Human
- Name
- iFluor 647
- Color
- Far-red
- Excitation⁄Emission (nm)
- 650/665
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-974 | Anti-CEACAM6 (Sulesomab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-975 | Anti-CEACAM6 (Sulesomab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-977 | Anti-CEACAM6 (Sulesomab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-978 | Anti-CEACAM6 (Sulesomab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-976 | Anti-CEACAM6 (Sulesomab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
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