t-Boc-Aminooxy-PEG2-azide (ADC-L-Y0252)

t-Boc-Aminooxy-PEG2-azide is a crosslinker containing an azide group and a t-Boc protected amine group. The azide group enables PEGylation via Click Chemistry. The protected aminooxy can be deprotected by mild acidic conditions and then can be reacted with an aldehyde or ketone group to form a stable oxime linkage. The BCN group can react with azide tagged biomolecules. The hydrophilic PEG spacer increases solubility in aqueous media.

CAS NO
252378-68-0

Description
t-Boc-Aminooxy-PEG2-azide is a crosslinker containing an azide group and a t-Boc protected amine group. The azide group enables PEGylation via Click Chemistry. The protected aminooxy can be deprotected by mild acidic conditions and then can be reacted with an aldehyde or ketone group to form a stable oxime linkage. The BCN group can react with azide tagged biomolecules. The hydrophilic PEG spacer increases solubility in aqueous media.

Molecular Weight
290.3

Purity
95%

Formula
C11H22N4O5

Group 1
Azide

Click Chemistry Group 1
Azide

PEG/Non-PEG
PEG

Cleavable/Non-cleavable
Non-cleavable

Group 2
COOR/Ester

Functional Group 2
COOR/Ester

Storage Condition
-20 ° C

Shipping
Ambient Temperature

For Research Use Only. NOT FOR CLINICAL USE.

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