This compound is a linker for bioconjugation. It is a PEG linker comprised of an octadecanedioic acid and a glutamic acid, which is also protected by a terminal t-butyl ester, with a terminal t-butyl ester and an azide. The t-butyl protected carboxyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
- Description
- This compound is a linker for bioconjugation. It is a PEG linker comprised of an octadecanedioic acid and a glutamic acid, which is also protected by a terminal t-butyl ester, with a terminal t-butyl ester and an azide. The t-butyl protected carboxyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
- Functional Group 1
- NH2/Amine
- Cleavable/Non-cleavable
- Non-cleavable
- Click Chemistry Group 2
- Azide
For Research Use Only. NOT FOR CLINICAL USE.
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