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- Anti-CD70 MAb (Clone 8)-iFluor® 546 Succinimidyl Ester
Anti-CD70 MAb (Clone 8)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14314)
This product is comprised of an Human Anti-CD70 lgG1 Antibody (Clone 8) labeled with iFluor® 546 Succinimidyl Ester. iFluor® 546 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD70
- Alternative Names
- CD70; CD70 molecule; CD27LG; TNFSF7; tumor necrosis factor (ligand) superfamily; member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily; member 7; CD27LG; TNFSF7;
- Overview
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
- Overview
- Human Anti-CD70 lgG1 Antibody (Clone 8)
- Species Reactivity
- Human
- Name
- iFluor® 546 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 541/557
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-376 | Anti-CD70-β-glucuronide-doxorubicin ADC-5 | β-glucuronide linker | doxorubicin |
| ADC-W-951 | Anti-CD70-SPDB-DM4 ADC-7 | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-952 | Anti-CD70-MC-MMAF ADC-7 | MC (maleimidocaproyl) | MMAF |
| ADC-W-567 | Anti-CD70-DM1 ADC | Noncleavable thioether linker | DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-446 | Anti-CD70-Mc-VC-PBD ADC-5 | mc-VC (maleimidocaproyl-valine-citrulline) | pyrrolobenzodiazepine (PBD) dimers |
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