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- Anti-DLL3-D6.5 ADC
Anti-DLL3-D6.5 ADC (CAT#: ADC-W-498)
This ADC product is comprised of an anti-DLL3 monoclonal antibody conjugated via a linker to D6.5.
- Product Information
- ADC Target
- ADC Antibody
- ADC payload drug
- Similar to
- SC16LD6.5(rovalpituzumab tesirine)
- Name
- DLL3
- Alternative Names
- DLL3; delta-like 3 (Drosophila); SCDO1; delta-like protein 3; delta3; drosophila Delta homolog 3;
- Target Entrez Gene ID
- 10683
- Target UniProt ID
- Q9NYJ7
- Overview
- This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
- Overview
- Anti-DLL3 Antibody
- Species Reactivity
- Human
- Name
- D6.5
- Description
- Pyrrolobenzodiazepine (PBD) dimmers are highly cytotoxic DNA cross-linking agents. PBDs exert their biological activity through covalent binding via their N10-C11imine/carbinolamine moieties to the C2-amino position of a guanine residue within the minor groove of DNA.
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-108 | Anti-DLL3-PBD dimers ADC-6 | pyrrolobenzodiazepine (PBD) dimers | |
| ADC-W-107 | Anti-DLL3-PBD dimers ADC-5 | pyrrolobenzodiazepine (PBD) dimers | |
| ADC-W-104 | Anti-DLL3-PBD dimers ADC-2 | pyrrolobenzodiazepine (PBD) dimers | |
| ADC-W-106 | Anti-DLL3-PBD dimers ADC-4 | pyrrolobenzodiazepine (PBD) dimers | |
| ADC-W-558 | Anti-DLL3-PBD ADC | pyrrolobenzodiazepine (PBD) dimers |
For Research Use Only. NOT FOR CLINICAL USE.
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