ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-S0277	N-Boc-PEG36-alcohol				95%		Inquiry
ADC-L-S0278	TBDMS-PEG5	134179-40-1		308.5	95%		Inquiry
ADC-L-S0279	THP-PEG3	11/3/2163		190.2	95%		Inquiry
ADC-L-S0280	THP-PEG4	60221-37-6		234.3	95%		Inquiry
ADC-L-S0281	THP-PEG5	128660-97-9		278.3	95%		Inquiry
ADC-L-S0282	THP-PEG6	146395-14-4		322.4	95%		Inquiry
ADC-L-S0283	THP-PEG7	42607-87-4		366.5	95%		Inquiry
ADC-L-S0284	THP-PEG9	658858-65-2		454.6	95%		Inquiry
ADC-L-S0285	THP-PEG12	92417-25-9		586.7	95%		Inquiry
ADC-L-S0286	THP-PEG8-Tos	669556-37-0		520.6	95%		Inquiry
ADC-L-S0287	Tr-PEG3	105589-77-3		348.4	95%		Inquiry
ADC-L-S0288	Tr-PEG4	133699-09-9		392.5	95%		Inquiry
ADC-L-S0289	Tr-PEG5	125274-16-0		436.6	95%		Inquiry
ADC-L-S0290	Tr-PEG6	141282-24-8		480.6	95%		Inquiry
ADC-L-S0291	Tr-PEG7	127999-16-0		524.7	95%		Inquiry
ADC-L-S0292	Tr-PEG9	1144113-16-5		612.8	95%		Inquiry
ADC-L-S0293	(4-methoxyphenyl)diphenylmethylamino-PEG7	2353409-88-6		597.8	95%		Inquiry
ADC-L-S0295	Tetraethylene glycol	25322-68-3		194.2	95%		Inquiry
ADC-L-S0296	Pentaethylene glycol	4792-15-8		238.3	95%		Inquiry
ADC-L-S0297	Hexaethylene glycol	2615-15-8		282.3	95%		Inquiry