ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-S0298	Heptaethylene glycol	5617-32-3		326.4	95%		Inquiry
ADC-L-S0299	Octanethyl glycol	5117-19-1		370.4	95%		Inquiry
ADC-L-S0300	Nonaethylene glycol	3386-18-3		414.5	95%		Inquiry
ADC-L-S0301	PEG11	5579-66-8		458.6	95%		Inquiry
ADC-L-S0302	PEG12	6809-70-7		502.6	95%		Inquiry
ADC-L-S0303	PEG13	1786286		546.7	95%		Inquiry
ADC-L-S0304	PEG14	17598-96-8		590.7	95%		Inquiry
ADC-L-S0305	PEG15	1189112-05-7		634.8	95%		Inquiry
ADC-L-S0306	PEG16	28821-35-4		678.8	95%		Inquiry
ADC-L-S0307	PEG17	4669-05-0		722.9	95%		Inquiry
ADC-L-S0308	PEG18	351342-04-6		766.9	95%		Inquiry
ADC-L-S0309	PEG21	351342-08-0		899.1	95%		Inquiry
ADC-L-S0310	PEG22	928211-42-1		943.1	95%		Inquiry
ADC-L-S0311	PEG23	2243942-52-9		1075.3	95%		Inquiry
ADC-L-S0312	t-Boc-Aminooxy-PEG2-alcohol	1807503-86-1		221.3	95%		Inquiry
ADC-L-S0313	t-Boc-Aminooxy-PEG3-alcohol	252378-66-8		265.3	95%		Inquiry
ADC-L-S0314	t-Boc-Aminooxy-PEG4-alcohol	918132-14-6		309.4	95%		Inquiry
ADC-L-S0315	t-Boc-Aminooxy-PEG8-alcohol	2353410-14-5		485.6	95%		Inquiry
ADC-L-S0316	Hydroxy-PEG1-methyl ester	93673-82-6		148.2	95%		Inquiry
ADC-L-S0317	Hydroxy-PEG2-methyl ester	457897-73-3		192.2	95%		Inquiry