ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-M0713	m-PEG6-(CH2)8-phosphonic acid ethyl ester	2028281-88-9		500.6	95%		Inquiry
ADC-L-M0714	m-PEG8-(CH2)12-phosphonic acid ethyl ester	2112737-70-7		644.8	95%		Inquiry
ADC-L-M0715	Propargyl-PEG3-phosphonic acid	1714139-62-4		252.2	95%		Inquiry
ADC-L-M0716	Propargyl-PEG3-phosphonic acid ethyl ester	1052678-30-4		308.3	95%		Inquiry
ADC-L-M0717	S-acetyl-PEG3-phosphonic acid ethyl ester				95%		Inquiry
ADC-L-M0719	Thiol-PEG3-phosphonic acid ethyl ester	1360716-43-3		330.4	95%		Inquiry
ADC-L-M0720	PEG3-bis(phosphonic acid diethyl ester)	500347-73-9		378.3	95%		Inquiry
ADC-L-M0721	PEG4-bis(phosphonic acid diethyl ester)	1807539-03-2		422.4	95%		Inquiry
ADC-L-M0722	PEG5-bis(phosphonic acid diethyl ester)	106338-06-1		466.4	95%		Inquiry
ADC-L-M0723	[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester	34008-16-7		332.3	95%		Inquiry
ADC-L-M0724	[4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester	720707-93-7		360.3	95%		Inquiry
ADC-L-M0725	[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester	1446282-35-4		388.4	95%		Inquiry
ADC-L-M0733	Propargyl-PEG3-triethoxysilane	2250216-92-1		419.6	95%		Inquiry
ADC-L-S0011	Azidoethyl-SS-ethylazide	352305-38-5		204.3	95%		Inquiry
ADC-L-S0020	Acid-PEG3-SS-PEG3-acid	2055014-98-5		474.6	95%		Inquiry
ADC-L-S0021	Acid-PEG4-S-S-PEG4-acid	2055015-40-0		562.7	95%		Inquiry
ADC-L-S0022	Acid-PEG6-SS-PEG6-acid	2055014-97-4		738.9	95%		Inquiry
ADC-L-S0028	N-(2,2,2-Trifluoroacetyl)-3-[(2-aminoethyl)dithio]propanoic acid	2401831-98-7		277.3	95%		Inquiry
ADC-L-S0029	Trifluoroacetamidoethyl-SS-propionic NHS ester	2380318-60-3		374.4	95%		Inquiry
ADC-L-S0031	m-PEG6-SS-PEG6-methyl	1007386-15-3		622.8	95%		Inquiry