DM1 (ADC-P-033)

ADCs Toxins, DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
  • CAS NO
  • 139504-50-0
  • Description
  • ADCs Toxins, DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
  • Classification
  • Microtubule Inhibitors
  • Molecular Weight
  • 738.29
  • Purity
  • 95%

For Research Use Only. NOT FOR CLINICAL USE.


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