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- Anti-CD33mAb-DOTA-SH ADC
Anti-CD33mAb-DOTA-SH ADC (CAT#: ADC-W-360)
This ADC product is comprised of an anti-CD33 monoclonal antibody conjugated via a DOTA-SH linker to a drug.
- Product Information
- ADC Target
- ADC Antibody
- ADC Linker
- Antibody clone #
- HuM195
- Name
- CD33
- Alternative Names
- CD33; CD33 molecule; p67; SIGLEC3; SIGLEC-3; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3;
- Target Entrez Gene ID
- 945
- Target UniProt ID
- P20138
- Overview
- CD33 or Siglec-3 is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It binds sialic acids, therefore is a member of the SIGLEC family of lectins.
- Overview
- Humanized Anti-CD33 lgG1 Antibody, clone # HuM195
- Clone #
- HuM195
- Species Reactivity
- Human
- Name
- DOTA-SH
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2540 | Anti-CD33 (Gemtuzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-480 | Anti-CD33-SPDB-DM4 ADC-6 | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-2538 | Anti-CD33 (Gemtuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-814 | Anti-CD33 (Lintuzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-2542 | Anti-CD33 (Gemtuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
For Research Use Only. NOT FOR CLINICAL USE.
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