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- Anti-LYPD3-lysine-toxophore ADC-1
Anti-LYPD3-lysine-toxophore ADC-1 (CAT#: ADC-W-110)
This ADC product is comprised of an anti-LYPD3 monoclonal antibody (clone M31-B01) conjugated via a lysine linker to toxophore.
- Product Information
- ADC Target
- ADC Antibody
- ADC Linker
- ADC payload drug
- Antibody clone #
- M31-B01
- Name
- LYPD3
- Alternative Names
- LYPD3; LY6/PLAUR Domain Containing 3;GPI-Anchored Metastasis-Associated Protein C4.4A Homolog;Matrigel-Induced Gene C4 Protein;MIG-C4;GPI-Anchored Metastasis-Associated Protein Homolog;Ly6/PLAUR Domain-Containing Protein 3;2310061G07Rik;
- Target Entrez Gene ID
- 27076
- Target UniProt ID
- 095274
- Overview
- This gene is a Protein Coding gene. GO annotations related to this gene include laminin binding. An important paralog of this gene is LYPD5.
- Overview
- Anti-LYPD3 antibody, clone # M31-B01
- Clone #
- M31-B01
- Species Reactivity
- Human
- Name
- lysine
- Description
- Noncleavable linkers, is considered noncleavable-meaning linker cleavage, and payload release does not depend on the differential properties between the plasma and some cytoplasmic compartments. Instead, the release of the cytotoxic drug is postulated to occur after internalization of the ADC via antigen-mediated endocytosis and delivery to lysosomal compartment, where the antibody is degraded to the level of amino acids through intracellular proteolytic degradation.
- Name
- toxophore loading
For Research Use Only. NOT FOR CLINICAL USE.
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Published Data
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Quick Links
Other Products
Same Target
Same Linker
Same Payload
| CAT# | Product Name | Linker | Payload |
| ADC-W-111 | Anti-LYPD3-lysine-toxophore ADC-2 | lysine | toxophore loading |
| ADC-W-561 | Anti-LYPD3-auristatin ADC | Auristatin |
| CAT# | Product Name | Linker | Payload |
| ADC-W-111 | Anti-LYPD3-lysine-toxophore ADC-2 | lysine | toxophore loading |
| CAT# | Product Name | Linker | Payload |
| ADC-W-111 | Anti-LYPD3-lysine-toxophore ADC-2 | lysine | toxophore loading |
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