CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-871-5806
Europe: 44-207-048-3343
Fax: 1-631-207-8356
Email:

CAR Targeting Carcinoma-specific Antigens

As a leading and reliable service provider, Creative Biolabs is well known worldwide for its breakthrough in CAR production system. Based on targeting carcinoma-specific antigens in the follow table, our outstanding scientists have constructed diverse CAR T cells or CAR NK cells targeting these antigens. In addition to these, Creative Biolabs can also customize CAR product according to your special requirements.

CAR Targeting Carcinoma-specific Antigens

Vicki Brower. The CAR T-Cell Race. The scientist. 2015

As a group of cancer, carcinoma usually starts from skin and spreads to other organs of the body. It accounts for 90% of all cancers, which mostly occurs in adults, with the DNA mutation as its main cause. Based on the tissue which cancer cells arise from, the primary carcinoma category includes breast cancer, prostate cancer, colorectal cancer, lung malignancy, adenocarcinomas, cervical carcinoma, melanoma and renal cell carcinoma. The most common symptom is lump under the skin, while there’re some other symptoms such as skin discolorations, pains. Although few strategies show effectiveness in carcinoma treatment, immunotherapy has performed great potential as a promising approach to treat carcinoma, such as CAR modified T cells or natural killer (NK) cells. Experts from Creative Biolabs can offer various CAR T cell or NK cells construction services according to your request.

Based on a great amount of experiments, we are confident our first-class CAR products can greatly accelerate your project process. Please feel free to contact us at any time.

Products against Carcinoma-specific antigens

Associated malignancy Target antigen Receptor type Product
Breast and others erb-B2 ScFv-CD28mut-CD3ζ Inquiry
erb-B2 ScFv-CD28-OX40-CD3ζ pCDCAR1 ErbB2 h(28OXζ), T
erb-B 2,3,4 ScFv-CD3ζ pCDCAR1 ErbB2 h(ζ), T
CEA ScFv-CD28-CD3ζ pCDCAR1 CEA h(28ζ), T
MUC1 ScFv-FcεRIγ pCDCAR1 MUC1 h(γ), T
LeY ScFv-CD3ξ pCDCAR1 LeY h(ζ), T
Prostate cancer erb-B2 ScFv-CD3ζ pCDCAR1 ErbB2 h(ζ), T
PSCA scFv-FcεRIγ pCDCAR1 PSCA h(FcεRIγ), T
PSMA
Colorectal cancer CEA ScFv-CD28-CD3ζ pCDCAR1 CEA h(28ζ), T
EGP-40 ScFv-CD28-CD3ζ vs. CD3ζ Inquiry
erb-B2 ScFV-CD28-FcεRIγ pCDCAR1 ErbB2 h(28FcεRIγ), T
Lung malignancy Her2/neu ScFv-CD3ζ pCDCAR1 ErbB2 h(ζ), T
Adenocarcinomas TAG-72 ScFv-FcεRIγ (alloantigen) pCDCAR1 TAG-72 h(γ), T
Cervical carcinoma CD44v7/8 ScFv-CD28-CD3ζ Inquiry
Melanoma GD3 ScFv-CD3ζ pCDCAR1 GD3 h(ζ), T
MAGE-A1 ScFv-CD4-CD3ζ Inquiry
Renal cell carcinoma CAIX CD3 ζ /CD137/CD28 pCDCAR1 CAIX h(ζ), T
CAIX CD3ζ(EBV) pCDCAR1 CAIX h(ζ), T
Epithelial derived tumors LeY ScFv-CD3ξ pCDCAR1 LeY h(ζ), T

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-048-3343

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